Peter paolella's Introduction to Molecular Biology
Introduction to Molecular Biology focuses on molecular biology concepts and less on expanded data and themes. It presents a solid framework of concepts to better prepare students for more detailed courses in molecular biology and genetics. W
ritten for science majors, this introductory, one-semester molecular biology text is designed for a sophomore-level course and assumes general biology and chemistry courses as a prerequisite.
The examination of structure at the microscopic scale, between micrometers and angstrom units, has changed dramatically in recent decades. Many new types of microscopy have emerged, notably the many scanning-probe designs, some of which also allow manipulation of atoms to form wanted structures, while others now permit direct observation of moving proteins in liquids. The traditional electron microscope is being revolutionized by the arrival of aberration correctors and monochromators, which bring the resolution below the Angstrom and electron-volt level. The "laboratory in a microscope" concept is rapidly evolving, as nanostructures are observed forming under controlled conditions at atomic resolution (the carbon nanotube being the most famous recent example). Electron holography and scanning transmission electron microscopy have become indispensable tools of the semiconductor industry. The oldest form of microscopy, optical microscopy, has been rejuvenated by the development of fluorescent, confocal, and two-photon variants. Analytical Scanning X-ray microscopes and Photoemission microscopes at synchrotons now routinely provide spatially resolved electronic structure maps. Tomographic imaging has vastly increased the information content of practically all forms of microscopy, as reflected in the award of a recent Nobel Prize. Molecular biology is benefiting enormously from progress in this technique. Most of these developments are responses to the urgent needs of researchers to characterize new useful nanostructures at the atomic level. In Science of Microscopy, comprehensive reviews set these innovations in the context of microscopy today. Each contribution presents a form of microscopy or occasionally a microscopic technique, and provides information about the instruments involved and their areas of application. The contributions are written in such a way that the reader can understand how the various instruments function, their strengths and weaknesses, and whether they are suitable for a particular scientific investigation. Science of Microscopy will be an indispensable guide to both a wide range of scientists in university laboratories and to engineers and scientists in industrial R&D departments. Key Features * Full-length essays on each type of instrument or technique * Applications to both materials science and the biomedical sciences * Essay-length tre
atment by respected experts in each field * Covers the latest developments as well as background information for the beginning microscopist
Nature is the international weekly journal of science: a magazine style journal that
publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.Peptide-Based Drug Design: Methods and Protocols
Description: Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transforming a promising protein fragment or stand-alone native peptide into a pharmaceutically acceptable composition. The volume delves into contemporary, cutting-edge subjects such as hit isolation and target validation, computer-aided design, sequence modifications to satisfy pharmacologists, in vivo stability and imaging, and the actual production of difficult sequences. Written in the highly successful Methods in Molecular Biology™ series format, chapters include readily reproducible, step-by-step laboratory protocols, lists of materials, and the Notes section, which highlights tips on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Peptide-Bas
ed Drug Design: Methods and Protocols shows its subject to be an independent science on the rise, and provides scientists with a clear, concise guide for continuing this vital research. 
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The science and business of biotechnology.
Nature Biotechnology devotes pages specifically to in-depth analysis of issues concerning biotechnology intellectual property case law and policy, together with breaking news on patents. Also included in each issue are key emerging areas such as computational biology and materials science.
Geographic Eligibility: USA, Canada, Selected International
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