Biology at the Single Molecule Level
This is the first book solely devoted to single-molecule biochemistry and molecular biology. Authors were selected on the basis of their contribution to this new and exciting field, and were asked to focus more on the biological problems that can be approached using single-molecule techniques rather than on the techniques per se. It is thought that such techniques will eventually dominate the physical characterization of biologically important macromolecules.Introduction to Bioinformatics: A Theoretical and Practical Approach
A comprehensible introduction to the key biological, mathematical, statistical, and computer concepts and tools behind bioinformatics. For physical scientists, the book provides a sound biological framework for understanding the questions a life scientist would ask in the context of currently available computational tools. For life scientists, a complete discussion of the UNIX operating system offers biologists graphical-user-interface comfort in a command-line environment, plus an understanding of the installation and management of UNIX-based software tools. In the applications sections the book provides a common meeting ground for life and physical scientists. Here they will find examples of the management and analysis of DNA sequencing projects, the modeling of DNA as a statistical series of patterns, various methods of pattern discovery, protein visualization, and the use of multiple sequence alignment to infer both functional and structural biological relationships. An accompanying CD contains several full and limited trial-versions of the programs discussed in the text, as well as a complete set of illustrations from each chapter suitable for lectures and presentations.An Introduction to Genetic Engineering
Des Nicholl presents a new, fully revised, and expanded edition of his popular undergraduate-level textbook. The book retains many of the features of the original edition and still offers a concise technical introduction to the subject of genetic engineering. It is divided into three main sections: basic molecular biology, methods of gene manipulation, and modern applications of genetic engineering. Applications covered in the book include genomics, protein engineering, gene therapy, cloning, transgenic animals and plants, and bioethics. An Introduction to Genetic Engineering is essential reading for undergraduate students of biotechnology, genetics, molecular biology, and biochemistry.
Proteomics for Biological Discovery
Written by recognized experts in the study of proteins, Proteomics for Biological Discovery begins by discussing the emergence of proteomics from genome sequencing projects and a summary of potential answers to be gained from proteome-level research.
- Presents a comprehensive and coherent review of the major issues faced in terms of technology development, bioinformatics, strategic approaches, and applications
- Chapters offer a rigorous overview with summary of limitations, emerging approaches, questions, and realistic future industry and basic science applications
- Discusses higher level integrative aspects, including technica l challenges and applications for drug discovery
- Accessible to the novice while providing experienced investigators essential informatio.
